STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOTCH1Notch receptor 1. (2551 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.993
MAML1
Mastermind like transcriptional coactivator 1.
   
 0.984
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.983
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.978
ENSCJAP00000072853
EGF-like domain-containing protein.
   
0.966
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.958
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.944
FBXW7
F-box and WD repeat domain containing 7.
    
 0.915
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.878
NCSTN
Nicastrin.
    
 0.878
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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