HECTD2 protein (Callithrix jacchus) - STRING interaction network

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HECTD2

Putative E3 ubiquitin-protein ligase HECTD2 isoform a. (776 aa)

Predicted Functional Partners:

TRIP12

0.687

UBE2L3

0.555

ISG15

0.527

PCGF5

0.524

PSMD4

0.514

NOC3L

0.508

ATG7

0.420

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	HECTD2	ENSCJAP00000044514	ENSCJAP00000020291	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	0.420
ATG7	ISG15	ENSCJAP00000044514	ENSCJAP00000021002	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	ISG15 ubiquitin like modifier.	0.546
ATG7	PSMD4	ENSCJAP00000044514	ENSCJAP00000062725	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	26S proteasome non-ATPase regulatory subunit 4.	0.618
ATG7	TRIP12	ENSCJAP00000044514	ENSCJAP00000024288	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Uncharacterized protein.	0.939
ATG7	UBE2L3	ENSCJAP00000044514	ENSCJAP00000067620	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family.	0.512
HECTD2	ATG7	ENSCJAP00000020291	ENSCJAP00000044514	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.420
HECTD2	ISG15	ENSCJAP00000020291	ENSCJAP00000021002	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	ISG15 ubiquitin like modifier.	0.527
HECTD2	NOC3L	ENSCJAP00000020291	ENSCJAP00000029088	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	Nucleolar complex protein 3 homolog.	0.508
HECTD2	PCGF5	ENSCJAP00000020291	ENSCJAP00000061711	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	RING-type domain-containing protein.	0.524
HECTD2	PSMD4	ENSCJAP00000020291	ENSCJAP00000062725	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	26S proteasome non-ATPase regulatory subunit 4.	0.514
HECTD2	TRIP12	ENSCJAP00000020291	ENSCJAP00000024288	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	Uncharacterized protein.	0.687
HECTD2	UBE2L3	ENSCJAP00000020291	ENSCJAP00000067620	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family.	0.555
ISG15	ATG7	ENSCJAP00000021002	ENSCJAP00000044514	ISG15 ubiquitin like modifier.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.546
ISG15	HECTD2	ENSCJAP00000021002	ENSCJAP00000020291	ISG15 ubiquitin like modifier.	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	0.527
ISG15	PSMD4	ENSCJAP00000021002	ENSCJAP00000062725	ISG15 ubiquitin like modifier.	26S proteasome non-ATPase regulatory subunit 4.	0.772
ISG15	TRIP12	ENSCJAP00000021002	ENSCJAP00000024288	ISG15 ubiquitin like modifier.	Uncharacterized protein.	0.871
ISG15	UBE2L3	ENSCJAP00000021002	ENSCJAP00000067620	ISG15 ubiquitin like modifier.	Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family.	0.408
NOC3L	HECTD2	ENSCJAP00000029088	ENSCJAP00000020291	Nucleolar complex protein 3 homolog.	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	0.508
PCGF5	HECTD2	ENSCJAP00000061711	ENSCJAP00000020291	RING-type domain-containing protein.	Putative E3 ubiquitin-protein ligase HECTD2 isoform a.	0.524
PSMD4	ATG7	ENSCJAP00000062725	ENSCJAP00000044514	26S proteasome non-ATPase regulatory subunit 4.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.618