| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BTLA | CD4 | ENSCJAP00000059299 | ENSCJAP00000043597 | B and T lymphocyte associated. | Ig-like domain-containing protein. | 0.482 |
| BTLA | CD40LG | ENSCJAP00000059299 | ENSCJAP00000056697 | B and T lymphocyte associated. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.491 |
| BTLA | CTLA4 | ENSCJAP00000059299 | ENSCJAP00000064098 | B and T lymphocyte associated. | Cytotoxic T-lymphocyte associated protein 4. | 0.700 |
| BTLA | ICOS | ENSCJAP00000059299 | ENSCJAP00000069147 | B and T lymphocyte associated. | Inducible T cell costimulator. | 0.648 |
| BTLA | TNFRSF18 | ENSCJAP00000059299 | ENSCJAP00000020913 | B and T lymphocyte associated. | GITR. | 0.751 |
| CD4 | BTLA | ENSCJAP00000043597 | ENSCJAP00000059299 | Ig-like domain-containing protein. | B and T lymphocyte associated. | 0.482 |
| CD4 | CD40LG | ENSCJAP00000043597 | ENSCJAP00000056697 | Ig-like domain-containing protein. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.955 |
| CD4 | CTLA4 | ENSCJAP00000043597 | ENSCJAP00000064098 | Ig-like domain-containing protein. | Cytotoxic T-lymphocyte associated protein 4. | 0.923 |
| CD4 | FOXP3 | ENSCJAP00000043597 | ENSCJAP00000056781 | Ig-like domain-containing protein. | Forkhead box P3. | 0.949 |
| CD4 | ICOS | ENSCJAP00000043597 | ENSCJAP00000069147 | Ig-like domain-containing protein. | Inducible T cell costimulator. | 0.871 |
| CD4 | TNFRSF18 | ENSCJAP00000043597 | ENSCJAP00000020913 | Ig-like domain-containing protein. | GITR. | 0.718 |
| CD4 | TNFRSF4 | ENSCJAP00000043597 | ENSCJAP00000020888 | Ig-like domain-containing protein. | TNF receptor superfamily member 4. | 0.559 |
| CD40LG | BTLA | ENSCJAP00000056697 | ENSCJAP00000059299 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | B and T lymphocyte associated. | 0.491 |
| CD40LG | CD4 | ENSCJAP00000056697 | ENSCJAP00000043597 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Ig-like domain-containing protein. | 0.955 |
| CD40LG | CTLA4 | ENSCJAP00000056697 | ENSCJAP00000064098 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Cytotoxic T-lymphocyte associated protein 4. | 0.852 |
| CD40LG | FOXP3 | ENSCJAP00000056697 | ENSCJAP00000056781 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Forkhead box P3. | 0.735 |
| CD40LG | ICOS | ENSCJAP00000056697 | ENSCJAP00000069147 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Inducible T cell costimulator. | 0.996 |
| CD40LG | TNFRSF18 | ENSCJAP00000056697 | ENSCJAP00000020913 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | GITR. | 0.796 |
| CD40LG | TNFRSF4 | ENSCJAP00000056697 | ENSCJAP00000020888 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF receptor superfamily member 4. | 0.575 |
| CD40LG | TNFSF11 | ENSCJAP00000056697 | ENSCJAP00000032488 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Tumor necrosis factor ligand superfamily member. | 0.600 |