| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACKR3 | CXCL12 | ENSCJAP00000040703 | ENSCJAP00000030009 | C-X-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. | 0.997 |
| ACKR3 | CXCR4 | ENSCJAP00000040703 | ENSCJAP00000022127 | C-X-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | 0.992 |
| CCR5 | CD4 | ENSCJAP00000053250 | ENSCJAP00000043597 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Ig-like domain-containing protein. | 0.980 |
| CCR5 | CXCL12 | ENSCJAP00000053250 | ENSCJAP00000030009 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. | 0.917 |
| CCR5 | CXCR1 | ENSCJAP00000053250 | ENSCJAP00000062523 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | C-X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.935 |
| CCR5 | CXCR4 | ENSCJAP00000053250 | ENSCJAP00000022127 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | 0.974 |
| CCR5 | GNAI1 | ENSCJAP00000053250 | ENSCJAP00000005923 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. | 0.946 |
| CCR5 | GNAI3 | ENSCJAP00000053250 | ENSCJAP00000005564 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(K) subunit alpha. | 0.946 |
| CCR5 | GNB1 | ENSCJAP00000053250 | ENSCJAP00000019968 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. | 0.928 |
| CCR5 | GNB4 | ENSCJAP00000053250 | ENSCJAP00000073409 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit beta-4. | 0.928 |
| CCR5 | GNG2 | ENSCJAP00000053250 | ENSCJAP00000061696 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.940 |
| CD4 | CCR5 | ENSCJAP00000043597 | ENSCJAP00000053250 | Ig-like domain-containing protein. | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | 0.980 |
| CD4 | CXCL12 | ENSCJAP00000043597 | ENSCJAP00000030009 | Ig-like domain-containing protein. | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. | 0.686 |
| CD4 | CXCR1 | ENSCJAP00000043597 | ENSCJAP00000062523 | Ig-like domain-containing protein. | C-X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.458 |
| CD4 | CXCR4 | ENSCJAP00000043597 | ENSCJAP00000022127 | Ig-like domain-containing protein. | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | 0.968 |
| CXCL12 | ACKR3 | ENSCJAP00000030009 | ENSCJAP00000040703 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. | C-X-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. | 0.997 |
| CXCL12 | CCR5 | ENSCJAP00000030009 | ENSCJAP00000053250 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | 0.917 |
| CXCL12 | CD4 | ENSCJAP00000030009 | ENSCJAP00000043597 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. | Ig-like domain-containing protein. | 0.686 |
| CXCL12 | CXCR1 | ENSCJAP00000030009 | ENSCJAP00000062523 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. | C-X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.915 |
| CXCL12 | CXCR4 | ENSCJAP00000030009 | ENSCJAP00000022127 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | 0.999 |
