ERBB3 protein (Callithrix jacchus) - STRING interaction network

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Score

ERBB3

Receptor tyrosine-protein kinase erbB-3 isoform 1. (1341 aa)

Predicted Functional Partners:

ERBB2

0.999

NRG1

0.999

EGF

0.995

NRG2

0.995

GRB2

0.994

SHC1

0.993

EGFR

0.992

PIK3R1

0.990

ERBB4

0.987

MET

0.984

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	EGFR	ENSCJAP00000007289	ENSCJAP00000074658	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	ERBB2	ENSCJAP00000007289	ENSCJAP00000001808	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.997
EGF	ERBB3	ENSCJAP00000007289	ENSCJAP00000022152	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor tyrosine-protein kinase erbB-3 isoform 1.	0.995
EGF	ERBB4	ENSCJAP00000007289	ENSCJAP00000069390	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.991
EGF	GRB2	ENSCJAP00000007289	ENSCJAP00000067776	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Growth factor receptor-bound protein 2 isoform 1.	0.849
EGF	MET	ENSCJAP00000007289	ENSCJAP00000009442	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.836
EGF	NRG1	ENSCJAP00000007289	ENSCJAP00000014285	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 1.	0.844
EGF	NRG2	ENSCJAP00000007289	ENSCJAP00000046561	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 2.	0.671
EGF	PIK3R1	ENSCJAP00000007289	ENSCJAP00000029505	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1.	0.676
EGF	SHC1	ENSCJAP00000007289	ENSCJAP00000016965	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	SHC-transforming protein 1 isoform 3.	0.663
EGFR	EGF	ENSCJAP00000074658	ENSCJAP00000007289	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	ERBB2	ENSCJAP00000074658	ENSCJAP00000001808	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.998
EGFR	ERBB3	ENSCJAP00000074658	ENSCJAP00000022152	Receptor protein-tyrosine kinase.	Receptor tyrosine-protein kinase erbB-3 isoform 1.	0.992
EGFR	ERBB4	ENSCJAP00000074658	ENSCJAP00000069390	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.915
EGFR	GRB2	ENSCJAP00000074658	ENSCJAP00000067776	Receptor protein-tyrosine kinase.	Growth factor receptor-bound protein 2 isoform 1.	0.999
EGFR	MET	ENSCJAP00000074658	ENSCJAP00000009442	Receptor protein-tyrosine kinase.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.940
EGFR	NRG1	ENSCJAP00000074658	ENSCJAP00000014285	Receptor protein-tyrosine kinase.	Neuregulin 1.	0.991
EGFR	NRG2	ENSCJAP00000074658	ENSCJAP00000046561	Receptor protein-tyrosine kinase.	Neuregulin 2.	0.988
EGFR	PIK3R1	ENSCJAP00000074658	ENSCJAP00000029505	Receptor protein-tyrosine kinase.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1.	0.992
EGFR	SHC1	ENSCJAP00000074658	ENSCJAP00000016965	Receptor protein-tyrosine kinase.	SHC-transforming protein 1 isoform 3.	0.998