STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZFP36ZFP36 ring finger protein. (332 aa)    
Predicted Functional Partners:
MAPKAPK2
MAPK activated protein kinase 2; Belongs to the protein kinase superfamily.
    
 0.972
EXOSC8
Exosome component 8.
   
  0.970
CNOT1
CCR4-NOT transcription complex subunit 1.
    
 0.933
XRN1
5'-3' exoribonuclease 1.
    
 0.857
DUSP1
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
 
 0.788
DCP2
M7GpppN-mRNA hydrolase isoform 1.
   
 0.744
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
    
 0.732
YWHAB
14-3-3 protein beta/alpha; Belongs to the 14-3-3 family.
   
 0.731
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
   
 0.719
FOS
Proto-oncogene c-Fos.
   
  
 0.696
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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