TDG protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TDG

G/T mismatch-specific thymine DNA glycosylase. (410 aa)

Predicted Functional Partners:

SMUG1

0.891

F7IG57_CALJA

0.858

SUMO2

0.855

SUMO3

0.830

MBD4

0.812

ENSCJAP00000061564

0.803

SUMO1

0.799

APEX1

0.796

CREBBP

0.793

OGG1

0.786

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APEX1	CREBBP	ENSCJAP00000017864	ENSCJAP00000036680	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	CREB-binding protein isoform a.	0.446
APEX1	MBD4	ENSCJAP00000017864	ENSCJAP00000031837	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.566
APEX1	OGG1	ENSCJAP00000017864	ENSCJAP00000029657	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	8-oxoguanine DNA glycosylase.	0.916
APEX1	SMUG1	ENSCJAP00000017864	ENSCJAP00000073371	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Single-strand selective monofunctional uracil DNA glycosylase isoform 1.	0.704
APEX1	TDG	ENSCJAP00000017864	ENSCJAP00000026754	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	G/T mismatch-specific thymine DNA glycosylase.	0.796
CREBBP	APEX1	ENSCJAP00000036680	ENSCJAP00000017864	CREB-binding protein isoform a.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.446
CREBBP	ENSCJAP00000061564	ENSCJAP00000036680	ENSCJAP00000061564	CREB-binding protein isoform a.	Small ubiquitin-related modifier.	0.490
CREBBP	F7IG57_CALJA	ENSCJAP00000036680	ENSCJAP00000026777	CREB-binding protein isoform a.	Small ubiquitin-related modifier.	0.490
CREBBP	SUMO1	ENSCJAP00000036680	ENSCJAP00000062736	CREB-binding protein isoform a.	Small ubiquitin-related modifier.	0.538
CREBBP	SUMO2	ENSCJAP00000036680	ENSCJAP00000063370	CREB-binding protein isoform a.	Small ubiquitin-related modifier.	0.487
CREBBP	SUMO3	ENSCJAP00000036680	ENSCJAP00000019420	CREB-binding protein isoform a.	Small ubiquitin-related modifier.	0.490
CREBBP	TDG	ENSCJAP00000036680	ENSCJAP00000026754	CREB-binding protein isoform a.	G/T mismatch-specific thymine DNA glycosylase.	0.793
ENSCJAP00000061564	CREBBP	ENSCJAP00000061564	ENSCJAP00000036680	Small ubiquitin-related modifier.	CREB-binding protein isoform a.	0.490
ENSCJAP00000061564	TDG	ENSCJAP00000061564	ENSCJAP00000026754	Small ubiquitin-related modifier.	G/T mismatch-specific thymine DNA glycosylase.	0.803
F7IG57_CALJA	CREBBP	ENSCJAP00000026777	ENSCJAP00000036680	Small ubiquitin-related modifier.	CREB-binding protein isoform a.	0.490
F7IG57_CALJA	TDG	ENSCJAP00000026777	ENSCJAP00000026754	Small ubiquitin-related modifier.	G/T mismatch-specific thymine DNA glycosylase.	0.858
MBD4	APEX1	ENSCJAP00000031837	ENSCJAP00000017864	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.566
MBD4	SMUG1	ENSCJAP00000031837	ENSCJAP00000073371	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	Single-strand selective monofunctional uracil DNA glycosylase isoform 1.	0.848
MBD4	TDG	ENSCJAP00000031837	ENSCJAP00000026754	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	G/T mismatch-specific thymine DNA glycosylase.	0.812
OGG1	APEX1	ENSCJAP00000029657	ENSCJAP00000017864	8-oxoguanine DNA glycosylase.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.916