node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADI1 | BHMT2 | ENSCJAP00000074800 | ENSCJAP00000036750 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. | 0.581 |
ADI1 | MAT1A | ENSCJAP00000074800 | ENSCJAP00000077350 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.511 |
ADI1 | MAT2A | ENSCJAP00000074800 | ENSCJAP00000045366 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.511 |
ADI1 | MTR | ENSCJAP00000074800 | ENSCJAP00000032605 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.581 |
ADI1 | TAT | ENSCJAP00000074800 | ENSCJAP00000027613 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.962 |
BHMT2 | ADI1 | ENSCJAP00000036750 | ENSCJAP00000074800 | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. | 0.581 |
BHMT2 | MAT1A | ENSCJAP00000036750 | ENSCJAP00000077350 | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.966 |
BHMT2 | MAT2A | ENSCJAP00000036750 | ENSCJAP00000045366 | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.965 |
BHMT2 | MTR | ENSCJAP00000036750 | ENSCJAP00000032605 | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.937 |
BHMT2 | TAT | ENSCJAP00000036750 | ENSCJAP00000027613 | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.932 |
GOT1 | GOT1L1 | ENSCJAP00000031333 | ENSCJAP00000004904 | Aspartate aminotransferase. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.913 |
GOT1 | GOT2 | ENSCJAP00000031333 | ENSCJAP00000020763 | Aspartate aminotransferase. | Aspartate aminotransferase. | 0.980 |
GOT1 | HPD | ENSCJAP00000031333 | ENSCJAP00000031117 | Aspartate aminotransferase. | 4-hydroxyphenylpyruvate dioxygenase. | 0.969 |
GOT1 | MAT1A | ENSCJAP00000031333 | ENSCJAP00000077350 | Aspartate aminotransferase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.566 |
GOT1 | MAT2A | ENSCJAP00000031333 | ENSCJAP00000045366 | Aspartate aminotransferase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.566 |
GOT1 | PAH | ENSCJAP00000031333 | ENSCJAP00000026378 | Aspartate aminotransferase. | Phenylalanine-4-hydroxylase. | 0.939 |
GOT1 | TAT | ENSCJAP00000031333 | ENSCJAP00000027613 | Aspartate aminotransferase. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.964 |
GOT1L1 | GOT1 | ENSCJAP00000004904 | ENSCJAP00000031333 | Glutamic-oxaloacetic transaminase 1 like 1. | Aspartate aminotransferase. | 0.913 |
GOT1L1 | GOT2 | ENSCJAP00000004904 | ENSCJAP00000020763 | Glutamic-oxaloacetic transaminase 1 like 1. | Aspartate aminotransferase. | 0.971 |
GOT1L1 | HPD | ENSCJAP00000004904 | ENSCJAP00000031117 | Glutamic-oxaloacetic transaminase 1 like 1. | 4-hydroxyphenylpyruvate dioxygenase. | 0.969 |