IL18BP protein (Callithrix jacchus) - STRING interaction network

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Score

IL18BP

Interleukin-18-binding protein isoform c. (198 aa)

Predicted Functional Partners:

IL18

0.909

IL37

0.831

IL18R1

0.644

IFNG

0.550

IGFLR1

0.524

TMEM156

0.505

TNFSF18

0.475

IL1RN

0.473

IL18RAP

0.470

TNFRSF12A

0.456

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IFNG	IL18	ENSCJAP00000056963	ENSCJAP00000022914	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	0.931
IFNG	IL18BP	ENSCJAP00000056963	ENSCJAP00000028218	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	Interleukin-18-binding protein isoform c.	0.550
IFNG	IL18R1	ENSCJAP00000056963	ENSCJAP00000015317	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	Interleukin-18 receptor 1.	0.418
IFNG	IL1RN	ENSCJAP00000056963	ENSCJAP00000068337	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	Interleukin-1.	0.522
IFNG	IL37	ENSCJAP00000056963	ENSCJAP00000031896	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	Interleukin 37.	0.453
IFNG	TMEM156	ENSCJAP00000056963	ENSCJAP00000001383	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	Transmembrane protein 156.	0.474
IGFLR1	IL18BP	ENSCJAP00000018605	ENSCJAP00000028218	IGF like family receptor 1.	Interleukin-18-binding protein isoform c.	0.524
IL18	IFNG	ENSCJAP00000022914	ENSCJAP00000056963	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.931
IL18	IL18BP	ENSCJAP00000022914	ENSCJAP00000028218	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-18-binding protein isoform c.	0.909
IL18	IL18R1	ENSCJAP00000022914	ENSCJAP00000015317	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-18 receptor 1.	0.996
IL18	IL18RAP	ENSCJAP00000022914	ENSCJAP00000051512	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin 18 receptor accessory protein.	0.994
IL18	IL1RN	ENSCJAP00000022914	ENSCJAP00000068337	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin-1.	0.465
IL18	IL37	ENSCJAP00000022914	ENSCJAP00000031896	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Interleukin 37.	0.539
IL18BP	IFNG	ENSCJAP00000028218	ENSCJAP00000056963	Interleukin-18-binding protein isoform c.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.550
IL18BP	IGFLR1	ENSCJAP00000028218	ENSCJAP00000018605	Interleukin-18-binding protein isoform c.	IGF like family receptor 1.	0.524
IL18BP	IL18	ENSCJAP00000028218	ENSCJAP00000022914	Interleukin-18-binding protein isoform c.	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	0.909
IL18BP	IL18R1	ENSCJAP00000028218	ENSCJAP00000015317	Interleukin-18-binding protein isoform c.	Interleukin-18 receptor 1.	0.644
IL18BP	IL18RAP	ENSCJAP00000028218	ENSCJAP00000051512	Interleukin-18-binding protein isoform c.	Interleukin 18 receptor accessory protein.	0.470
IL18BP	IL1RN	ENSCJAP00000028218	ENSCJAP00000068337	Interleukin-18-binding protein isoform c.	Interleukin-1.	0.473
IL18BP	IL37	ENSCJAP00000028218	ENSCJAP00000031896	Interleukin-18-binding protein isoform c.	Interleukin 37.	0.831