STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRTProtein tyrosine phosphatase receptor type T. (1414 aa)    
Predicted Functional Partners:
SKAP2
Src kinase associated phosphoprotein 2.
   
 
 0.553
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.517
CDH12
Cadherin-12 preproprotein; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.509
NRSN1
Neurensin-1.
   
  
 0.504
ADGRB3
Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.466
GRB2
Growth factor receptor-bound protein 2 isoform 1.
   
 0.465
FRAS1
Fraser extracellular matrix complex subunit 1.
   
 
 0.458
KIT
Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...]
   
 0.457
LRIT3
Leucine rich repeat, Ig-like and transmembrane domains 3.
    
  0.455
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
    
  0.455
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.