Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANGPTL3 | APOB | ENSCJAP00000030317 | ENSCJAP00000014061 | Angiopoietin like 3. | Apolipoprotein B. | 0.773 |
ANGPTL3 | PCSK9 | ENSCJAP00000030317 | ENSCJAP00000076181 | Angiopoietin like 3. | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] | 0.776 |
APOB | ANGPTL3 | ENSCJAP00000014061 | ENSCJAP00000030317 | Apolipoprotein B. | Angiopoietin like 3. | 0.773 |
APOB | EGF | ENSCJAP00000014061 | ENSCJAP00000007289 | Apolipoprotein B. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.657 |
APOB | HMGCR | ENSCJAP00000014061 | ENSCJAP00000031281 | Apolipoprotein B. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.796 |
APOB | LDLR | ENSCJAP00000014061 | ENSCJAP00000051207 | Apolipoprotein B. | Low density lipoprotein receptor. | 0.650 |
APOB | LRP8 | ENSCJAP00000014061 | ENSCJAP00000050657 | Apolipoprotein B. | LDL receptor related protein 8. | 0.740 |
APOB | PCSK9 | ENSCJAP00000014061 | ENSCJAP00000076181 | Apolipoprotein B. | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] | 0.925 |
APOB | VLDLR | ENSCJAP00000014061 | ENSCJAP00000020067 | Apolipoprotein B. | Very low-density lipoprotein receptor isoform a. | 0.892 |
EGF | APOB | ENSCJAP00000007289 | ENSCJAP00000014061 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Apolipoprotein B. | 0.657 |
EGF | PCSK9 | ENSCJAP00000007289 | ENSCJAP00000076181 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] | 0.766 |
EGF | VLDLR | ENSCJAP00000007289 | ENSCJAP00000020067 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Very low-density lipoprotein receptor isoform a. | 0.412 |
GOLPH3 | PCSK9 | ENSCJAP00000055671 | ENSCJAP00000076181 | Golgi phosphoprotein 3. | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] | 0.791 |
GOLPH3L | PCSK9 | ENSCJAP00000073582 | ENSCJAP00000076181 | Golgi phosphoprotein 3-like. | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] | 0.791 |
HMGCR | APOB | ENSCJAP00000031281 | ENSCJAP00000014061 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Apolipoprotein B. | 0.796 |
HMGCR | PCSK9 | ENSCJAP00000031281 | ENSCJAP00000076181 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] | 0.830 |
IGHE | PCSK9 | ENSCJAP00000052182 | ENSCJAP00000076181 | Immunoglobulin heavy constant epsilon. | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] | 0.844 |
LDLR | APOB | ENSCJAP00000051207 | ENSCJAP00000014061 | Low density lipoprotein receptor. | Apolipoprotein B. | 0.650 |
LDLR | PCSK9 | ENSCJAP00000051207 | ENSCJAP00000076181 | Low density lipoprotein receptor. | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] | 0.835 |
LRP8 | APOB | ENSCJAP00000050657 | ENSCJAP00000014061 | LDL receptor related protein 8. | Apolipoprotein B. | 0.740 |
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