EYA2 protein (Callithrix jacchus) - STRING interaction network

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Score

EYA2

Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (590 aa)

Predicted Functional Partners:

SIX1

0.867

SIX4

0.752

SIX2

0.715

SIX5

0.603

EYA3

0.579

MRE11

0.562

SIX3

0.557

ANHX

0.557

SIX6

0.557

ATM

0.556

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANHX	EYA2	ENSCJAP00000004332	ENSCJAP00000031081	Anomalous homeobox.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.557
ANHX	EYA3	ENSCJAP00000004332	ENSCJAP00000017481	Anomalous homeobox.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.557
ATM	EYA2	ENSCJAP00000018844	ENSCJAP00000031081	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.556
ATM	EYA3	ENSCJAP00000018844	ENSCJAP00000017481	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.585
ATM	MRE11	ENSCJAP00000018844	ENSCJAP00000007368	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.998
EYA2	ANHX	ENSCJAP00000031081	ENSCJAP00000004332	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Anomalous homeobox.	0.557
EYA2	ATM	ENSCJAP00000031081	ENSCJAP00000018844	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.556
EYA2	EYA3	ENSCJAP00000031081	ENSCJAP00000017481	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.579
EYA2	MRE11	ENSCJAP00000031081	ENSCJAP00000007368	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.562
EYA2	SIX1	ENSCJAP00000031081	ENSCJAP00000053864	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX1.	0.867
EYA2	SIX2	ENSCJAP00000031081	ENSCJAP00000072397	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX2.	0.715
EYA2	SIX3	ENSCJAP00000031081	ENSCJAP00000001262	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 3.	0.557
EYA2	SIX4	ENSCJAP00000031081	ENSCJAP00000035525	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 4.	0.752
EYA2	SIX5	ENSCJAP00000031081	ENSCJAP00000057297	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 5.	0.603
EYA2	SIX6	ENSCJAP00000031081	ENSCJAP00000035491	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 6.	0.557
EYA3	ANHX	ENSCJAP00000017481	ENSCJAP00000004332	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Anomalous homeobox.	0.557
EYA3	ATM	ENSCJAP00000017481	ENSCJAP00000018844	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.585
EYA3	EYA2	ENSCJAP00000017481	ENSCJAP00000031081	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.579
EYA3	MRE11	ENSCJAP00000017481	ENSCJAP00000007368	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.587
EYA3	SIX1	ENSCJAP00000017481	ENSCJAP00000053864	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Homeobox protein SIX1.	0.852