STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANGPTL2Angiopoietin-related protein 2. (493 aa)    
Predicted Functional Partners:
SCUBE3
Signal peptide, CUB domain and EGF like domain containing 3.
   
 0.625
TEK
TEK receptor tyrosine kinase.
   
 0.599
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
   
 0.586
AVIL
Advillin.
   
 
 0.518
DUSP11
Dual specificity phosphatase 11.
      
 0.499
FBLN5
Fibulin 5.
   
 0.478
ENSCJAP00000063656
Fib_alpha domain-containing protein.
 
 
  
 0.469
PPP1R12B
Protein phosphatase 1 regulatory subunit.
    
 
 0.448
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
  
 
 0.440
ANGPTL8
Hepatocellular carcinoma-associated protein TD26.
    
 0.433
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.