| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSCJAP00000069131 | PARP1 | ENSCJAP00000069131 | ENSCJAP00000072405 | DTHCT domain-containing protein. | Poly [ADP-ribose] polymerase. | 0.624 |
| ENSCJAP00000069131 | PCNA | ENSCJAP00000069131 | ENSCJAP00000067013 | DTHCT domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.608 |
| ENSCJAP00000069131 | TOP1 | ENSCJAP00000069131 | ENSCJAP00000033572 | DTHCT domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.891 |
| ENSCJAP00000069131 | TOP2B | ENSCJAP00000069131 | ENSCJAP00000007316 | DTHCT domain-containing protein. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.926 |
| MUS81 | PARP1 | ENSCJAP00000003437 | ENSCJAP00000072405 | MUS81 structure-specific endonuclease subunit. | Poly [ADP-ribose] polymerase. | 0.440 |
| MUS81 | PCNA | ENSCJAP00000003437 | ENSCJAP00000067013 | MUS81 structure-specific endonuclease subunit. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.835 |
| MUS81 | RAD52 | ENSCJAP00000003437 | ENSCJAP00000001094 | MUS81 structure-specific endonuclease subunit. | RAD52 homolog, DNA repair protein. | 0.945 |
| MUS81 | RNASEH2A | ENSCJAP00000003437 | ENSCJAP00000008906 | MUS81 structure-specific endonuclease subunit. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.499 |
| MUS81 | TDP1 | ENSCJAP00000003437 | ENSCJAP00000032563 | MUS81 structure-specific endonuclease subunit. | Tyrosyl-DNA phosphodiesterase 1. | 0.786 |
| MUS81 | TOP1 | ENSCJAP00000003437 | ENSCJAP00000033572 | MUS81 structure-specific endonuclease subunit. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.858 |
| PARP1 | ENSCJAP00000069131 | ENSCJAP00000072405 | ENSCJAP00000069131 | Poly [ADP-ribose] polymerase. | DTHCT domain-containing protein. | 0.624 |
| PARP1 | MUS81 | ENSCJAP00000072405 | ENSCJAP00000003437 | Poly [ADP-ribose] polymerase. | MUS81 structure-specific endonuclease subunit. | 0.440 |
| PARP1 | PCNA | ENSCJAP00000072405 | ENSCJAP00000067013 | Poly [ADP-ribose] polymerase. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.960 |
| PARP1 | RAD52 | ENSCJAP00000072405 | ENSCJAP00000001094 | Poly [ADP-ribose] polymerase. | RAD52 homolog, DNA repair protein. | 0.680 |
| PARP1 | TDP1 | ENSCJAP00000072405 | ENSCJAP00000032563 | Poly [ADP-ribose] polymerase. | Tyrosyl-DNA phosphodiesterase 1. | 0.581 |
| PARP1 | TOP1 | ENSCJAP00000072405 | ENSCJAP00000033572 | Poly [ADP-ribose] polymerase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.912 |
| PARP1 | TOP2A | ENSCJAP00000072405 | ENSCJAP00000024876 | Poly [ADP-ribose] polymerase. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.624 |
| PARP1 | TOP2B | ENSCJAP00000072405 | ENSCJAP00000007316 | Poly [ADP-ribose] polymerase. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.689 |
| PCNA | ENSCJAP00000069131 | ENSCJAP00000067013 | ENSCJAP00000069131 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DTHCT domain-containing protein. | 0.608 |
| PCNA | MUS81 | ENSCJAP00000067013 | ENSCJAP00000003437 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | MUS81 structure-specific endonuclease subunit. | 0.835 |
