STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NR3C1Nuclear receptor subfamily 3 group c member 1; Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA [...] (777 aa)    
Predicted Functional Partners:
NCOA1
Nuclear receptor coactivator 1
   
 0.991
ENSCJAP00000018243
Heat shock protein 90 alpha family class a member 1; Uncharacterized protein
    
 0.991
NCOA2
Nuclear receptor coactivator 2
   
 0.990
FKBP5
FK506-binding protein 4/5; Peptidylprolyl isomerase; FK506 binding protein 5
    
 0.987
FKBP4
FK506-binding protein 4/5; Peptidylprolyl isomerase; FK506 binding protein 4, 59kDa
    
 0.976
NCOR1
Nuclear receptor corepressor 1
   
 0.975
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
   
 0.973
CREBBP
E1A/CREB-binding protein; CREB binding protein
   
 0.954
HSP90AA1
Heat shock protein 90 alpha family class A member 1
    
 0.953
ENSCJAP00000046123
annotation not available
    
 0.953
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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