STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPMT1Protein tyrosine phosphatase mitochondrial 1. (200 aa)    
Predicted Functional Partners:
TAMM41
Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.
      
 0.939
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5.
      
 0.770
AGPAT4
1-acyl-sn-glycerol-3-phosphate acyltransferase delta.
      
 0.701
NDUFS3
NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family.
 
 
  
 0.655
TAZ
Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism.
      
 0.608
GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial.
      
 0.581
EXD2
Exonuclease 3'-5' domain-containing protein 2 isoform 1.
      
 0.562
PGS1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
      
 0.554
CRLS1
Cardiolipin synthase isoform 1.
      
 0.534
DOLPP1
Dolichyldiphosphatase 1; Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity); Belongs to the dolichyldiphosphatase family.
   
  
 0.468
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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