STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KNL1Kinetochore scaffold 1. (2180 aa)    
Predicted Functional Partners:
WRN
WRN RecQ like helicase.
   
 0.978
SPC24
SPC24 component of NDC80 kinetochore complex.
   
 0.975
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.969
BUB1B
Uncharacterized protein.
   
 0.969
NSL1
Kinetochore-associated protein NSL1 homolog isoform 1.
   
 0.947
MIS12
MIS12 kinetochore complex component.
   
 0.934
ZWINT
ZW10 interacting kinetochore protein.
   
 
 0.921
DSN1
DSN1 component of MIS12 kinetochore complex.
    
 0.918
XRCC3
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.
   
 0.915
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.895
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.