STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY1Sprouty RTK signaling antagonist 1. (356 aa)    
Predicted Functional Partners:
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.735
GRB2
Growth factor receptor-bound protein 2 isoform 1.
    
 
 0.735
CNPY1
Canopy FGF signaling regulator 1.
      
 0.690
CBLB
Cbl proto-oncogene B.
    
 0.649
CBLC
Cbl proto-oncogene C.
    
 0.637
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
     
 0.587
ETV5
ETS translocation variant 5.
      
 0.585
PAX8
Paired box 8.
      
 0.581
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 
 0.577
EN1
Homeobox protein engrailed-like.
      
 0.563
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.