STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACSSacsin molecular chaperone. (4579 aa)    
Predicted Functional Partners:
SERTAD4
SERTA domain-containing protein 4.
    
 0.806
NBEAL1
Neurobeachin like 1.
   
  
 0.788
PROSER1
Proline and serine-rich protein 1.
    
 0.780
INCENP
Inner centromere protein.
   
 0.774
DIABLO
Diablo homolog, mitochondrial isoform 1.
    
 0.756
ZBTB44
Zinc finger and BTB domain containing 44.
     
 0.718
AURKC
Aurora kinase C isoform 1; Belongs to the protein kinase superfamily.
   
 0.692
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.692
AURKB
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 0.692
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
   
 0.664
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.