STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SREBF1Sterol regulatory element binding transcription factor 1. (1178 aa)    
Predicted Functional Partners:
SCAP
SREBF chaperone.
   
 0.961
PPARGC1B
Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 1.
    
 0.951
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.874
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.844
KPNB1
Karyopherin subunit beta 1.
    
 0.837
LMNA
Uncharacterized protein; Belongs to the intermediate filament family.
    
 
 0.819
MBTPS2
Membrane bound transcription factor peptidase, site 2.
    
 0.790
ACACA
Acetyl-CoA carboxylase 1 isoform 1.
     
 0.790
FBXW7
F-box and WD repeat domain containing 7.
    
 0.780
MED15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.773
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.