| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAJA-DRA | CD4 | ENSCJAP00000066980 | ENSCJAP00000043597 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. | Ig-like domain-containing protein. | 0.989 |
| CAJA-DRA | HLA-DQA2 | ENSCJAP00000066980 | ENSCJAP00000002901 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. | Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. | 0.685 |
| CAJA-DRA | IFNG | ENSCJAP00000066980 | ENSCJAP00000056963 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.412 |
| CAJA-DRA | LCK | ENSCJAP00000066980 | ENSCJAP00000001648 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. | Tyrosine-protein kinase. | 0.465 |
| CAJA-DRA | ZAP70 | ENSCJAP00000066980 | ENSCJAP00000021145 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. | Zeta chain of T cell receptor associated protein kinase 70. | 0.506 |
| CCR5 | CD4 | ENSCJAP00000053250 | ENSCJAP00000043597 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Ig-like domain-containing protein. | 0.980 |
| CCR5 | CD8A | ENSCJAP00000053250 | ENSCJAP00000035988 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | CD8a molecule. | 0.430 |
| CCR5 | CXCR4 | ENSCJAP00000053250 | ENSCJAP00000022127 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | 0.974 |
| CCR5 | IFNG | ENSCJAP00000053250 | ENSCJAP00000056963 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.832 |
| CD4 | CAJA-DRA | ENSCJAP00000043597 | ENSCJAP00000066980 | Ig-like domain-containing protein. | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. | 0.989 |
| CD4 | CCR5 | ENSCJAP00000043597 | ENSCJAP00000053250 | Ig-like domain-containing protein. | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | 0.980 |
| CD4 | CD8A | ENSCJAP00000043597 | ENSCJAP00000035988 | Ig-like domain-containing protein. | CD8a molecule. | 0.992 |
| CD4 | CD8B | ENSCJAP00000043597 | ENSCJAP00000035967 | Ig-like domain-containing protein. | Ig-like domain-containing protein. | 0.967 |
| CD4 | CXCR4 | ENSCJAP00000043597 | ENSCJAP00000022127 | Ig-like domain-containing protein. | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | 0.968 |
| CD4 | HLA-DQA2 | ENSCJAP00000043597 | ENSCJAP00000002901 | Ig-like domain-containing protein. | Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. | 0.978 |
| CD4 | IFNG | ENSCJAP00000043597 | ENSCJAP00000056963 | Ig-like domain-containing protein. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.966 |
| CD4 | IL16 | ENSCJAP00000043597 | ENSCJAP00000055135 | Ig-like domain-containing protein. | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. | 0.976 |
| CD4 | LCK | ENSCJAP00000043597 | ENSCJAP00000001648 | Ig-like domain-containing protein. | Tyrosine-protein kinase. | 0.999 |
| CD4 | ZAP70 | ENSCJAP00000043597 | ENSCJAP00000021145 | Ig-like domain-containing protein. | Zeta chain of T cell receptor associated protein kinase 70. | 0.985 |
| CD8A | CCR5 | ENSCJAP00000035988 | ENSCJAP00000053250 | CD8a molecule. | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | 0.430 |
