DRD3 protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DRD3

Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)

Predicted Functional Partners:

DRD4

0.974

GNB4

0.880

GNG2

0.879

GNAI3

0.867

GNAI1

0.867

GNB1

0.860

GNAI2

0.846

GNB2

0.844

GNG4

0.844

GNB3

0.841

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD3	DRD4	ENSCJAP00000043693	ENSCJAP00000022145	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.974
DRD3	GNAI1	ENSCJAP00000043693	ENSCJAP00000005923	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	0.867
DRD3	GNAI2	ENSCJAP00000043693	ENSCJAP00000049315	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.	0.846
DRD3	GNAI3	ENSCJAP00000043693	ENSCJAP00000005564	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.867
DRD3	GNB1	ENSCJAP00000043693	ENSCJAP00000019968	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.860
DRD3	GNB2	ENSCJAP00000043693	ENSCJAP00000027836	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.844
DRD3	GNB3	ENSCJAP00000043693	ENSCJAP00000013981	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.841
DRD3	GNB4	ENSCJAP00000043693	ENSCJAP00000073409	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit beta-4.	0.880
DRD3	GNG2	ENSCJAP00000043693	ENSCJAP00000061696	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.879
DRD3	GNG4	ENSCJAP00000043693	ENSCJAP00000076465	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.844
DRD4	DRD3	ENSCJAP00000022145	ENSCJAP00000043693	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.974
DRD4	GNAI1	ENSCJAP00000022145	ENSCJAP00000005923	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	0.837
DRD4	GNAI2	ENSCJAP00000022145	ENSCJAP00000049315	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.	0.837
DRD4	GNAI3	ENSCJAP00000022145	ENSCJAP00000005564	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.837
DRD4	GNB1	ENSCJAP00000022145	ENSCJAP00000019968	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.814
DRD4	GNB2	ENSCJAP00000022145	ENSCJAP00000027836	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.814
DRD4	GNB3	ENSCJAP00000022145	ENSCJAP00000013981	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.832
DRD4	GNB4	ENSCJAP00000022145	ENSCJAP00000073409	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit beta-4.	0.814
DRD4	GNG2	ENSCJAP00000022145	ENSCJAP00000061696	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.840
DRD4	GNG4	ENSCJAP00000022145	ENSCJAP00000076465	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.840