| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CGA | FSHB | ENSCJAP00000001086 | ENSCJAP00000074962 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Follicle stimulating hormone beta subunit. | 0.948 |
| CGA | GPHB5 | ENSCJAP00000001086 | ENSCJAP00000035804 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Glycoprotein hormone subunit beta 5. | 0.731 |
| CGA | TSHB | ENSCJAP00000001086 | ENSCJAP00000077018 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Thyroid stimulating hormone subunit beta. | 0.993 |
| CGA | TSHR | ENSCJAP00000001086 | ENSCJAP00000031540 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.877 |
| ENSCJAP00000067849 | TSHR | ENSCJAP00000067849 | ENSCJAP00000031540 | Ig-like domain-containing protein. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.900 |
| FSHB | CGA | ENSCJAP00000074962 | ENSCJAP00000001086 | Follicle stimulating hormone beta subunit. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.948 |
| FSHB | TSHR | ENSCJAP00000074962 | ENSCJAP00000031540 | Follicle stimulating hormone beta subunit. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.822 |
| GNAQ | GNAS | ENSCJAP00000005953 | ENSCJAP00000035246 | Guanine nucleotide-binding protein G(Q) subunit alpha. | GNAS complex locus. | 0.609 |
| GNAQ | TSHR | ENSCJAP00000005953 | ENSCJAP00000031540 | Guanine nucleotide-binding protein G(Q) subunit alpha. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.936 |
| GNAS | GNAQ | ENSCJAP00000035246 | ENSCJAP00000005953 | GNAS complex locus. | Guanine nucleotide-binding protein G(Q) subunit alpha. | 0.609 |
| GNAS | LOC103787209 | ENSCJAP00000035246 | ENSCJAP00000071666 | GNAS complex locus. | Protein NESP55 isoform NESP55. | 0.917 |
| GNAS | TSHR | ENSCJAP00000035246 | ENSCJAP00000031540 | GNAS complex locus. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.969 |
| GPHB5 | CGA | ENSCJAP00000035804 | ENSCJAP00000001086 | Glycoprotein hormone subunit beta 5. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.731 |
| GPHB5 | TSHB | ENSCJAP00000035804 | ENSCJAP00000077018 | Glycoprotein hormone subunit beta 5. | Thyroid stimulating hormone subunit beta. | 0.416 |
| GPHB5 | TSHR | ENSCJAP00000035804 | ENSCJAP00000031540 | Glycoprotein hormone subunit beta 5. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.969 |
| LOC103787209 | GNAS | ENSCJAP00000071666 | ENSCJAP00000035246 | Protein NESP55 isoform NESP55. | GNAS complex locus. | 0.917 |
| LOC103787209 | TSHR | ENSCJAP00000071666 | ENSCJAP00000031540 | Protein NESP55 isoform NESP55. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.905 |
| TG | TPO | ENSCJAP00000008448 | ENSCJAP00000021336 | Thyroglobulin. | Thyroid peroxidase. | 0.927 |
| TG | TSHB | ENSCJAP00000008448 | ENSCJAP00000077018 | Thyroglobulin. | Thyroid stimulating hormone subunit beta. | 0.763 |
| TG | TSHR | ENSCJAP00000008448 | ENSCJAP00000031540 | Thyroglobulin. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.871 |