STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (962 aa)    
Predicted Functional Partners:
SCD5
Stearoyl-CoA desaturase 5 isoform a; Belongs to the fatty acid desaturase type 1 family.
      
 0.744
HP
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.729
APOA2
Apolipoprotein A-II preproprotein.
   
 
 0.682
SERPINA2
Serpin family A member 2 (gene/pseudogene); Belongs to the serpin family.
   
 
 0.682
CD4
Ig-like domain-containing protein.
    
 0.677
HRG
Histidine rich glycoprotein.
   
 0.663
CXCR4
C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...]
    
 0.651
PPP2R3C
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma.
    
 
 0.651
VTN
SMB domain-containing protein.
   
 0.644
PLG
Plasminogen; Belongs to the peptidase S1 family.
   
 0.643
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.