STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4BPAComplement component 4 binding protein alpha. (599 aa)    
Predicted Functional Partners:
C4BPB
Complement component 4 binding protein beta.
 
 
0.976
LOC100411501
Uncharacterized protein.
   
 0.968
C3
Complement C3.
   
 0.673
DPYS
Dihydropyrimidinase.
   
 
 0.587
C8G
Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.
      
 0.563
CFI
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.558
C1S
Complement C1s subcomponent; Belongs to the peptidase S1 family.
   
 0.526
SAA1
Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex.
   
  
 0.524
RNF25
E3 ubiquitin-protein ligase RNF25.
      
 0.511
CD19
B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...]
   
 0.491
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.