GGH protein (Callithrix jacchus) - STRING interaction network

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Score

GGH

Folate gamma-glutamyl hydrolase. (318 aa)

Predicted Functional Partners:

FPGS

0.947

DHFR

0.937

DHFR2

0.914

GCSH

0.733

SLC19A1

0.571

POLR2G

0.562

GART

0.553

ARL13B

0.553

RFC1

0.539

TPMT

0.527

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL13B	GGH	ENSCJAP00000069148	ENSCJAP00000048029	ADP ribosylation factor like GTPase 13B.	Folate gamma-glutamyl hydrolase.	0.553
DHFR	DHFR2	ENSCJAP00000047458	ENSCJAP00000061963	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.901
DHFR	FPGS	ENSCJAP00000047458	ENSCJAP00000036943	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.970
DHFR	GART	ENSCJAP00000047458	ENSCJAP00000047303	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.968
DHFR	GCSH	ENSCJAP00000047458	ENSCJAP00000052916	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Lipoyl-binding domain-containing protein.	0.580
DHFR	GGH	ENSCJAP00000047458	ENSCJAP00000048029	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Folate gamma-glutamyl hydrolase.	0.937
DHFR2	DHFR	ENSCJAP00000061963	ENSCJAP00000047458	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	0.901
DHFR2	FPGS	ENSCJAP00000061963	ENSCJAP00000036943	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.970
DHFR2	GART	ENSCJAP00000061963	ENSCJAP00000047303	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.968
DHFR2	GCSH	ENSCJAP00000061963	ENSCJAP00000052916	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Lipoyl-binding domain-containing protein.	0.580
DHFR2	GGH	ENSCJAP00000061963	ENSCJAP00000048029	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Folate gamma-glutamyl hydrolase.	0.914
FPGS	DHFR	ENSCJAP00000036943	ENSCJAP00000047458	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	0.970
FPGS	DHFR2	ENSCJAP00000036943	ENSCJAP00000061963	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.970
FPGS	GART	ENSCJAP00000036943	ENSCJAP00000047303	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.671
FPGS	GGH	ENSCJAP00000036943	ENSCJAP00000048029	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Folate gamma-glutamyl hydrolase.	0.947
FPGS	RFC1	ENSCJAP00000036943	ENSCJAP00000038500	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Replication factor C subunit 1.	0.471
GART	DHFR	ENSCJAP00000047303	ENSCJAP00000047458	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	0.968
GART	DHFR2	ENSCJAP00000047303	ENSCJAP00000061963	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.968
GART	FPGS	ENSCJAP00000047303	ENSCJAP00000036943	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.671
GART	GCSH	ENSCJAP00000047303	ENSCJAP00000052916	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Lipoyl-binding domain-containing protein.	0.844