STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (400 aa)    
Predicted Functional Partners:
TECR
Trans-2,3-enoyl-CoA reductase.
   
 0.846
TECRL
S5A_REDUCTASE domain-containing protein.
   
 0.798
NPC2
NPC intracellular cholesterol transporter 2.
      
 0.635
ENSCJAP00000065535
Uncharacterized protein.
   
 0.610
HSD17B12
Estradiol 17-beta-dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.610
HSD17B3
Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.602
SLC35D2
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter.
   
 0.602
HSDL1
Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.602
NCLN
Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
      
 0.574
PLEKHG1
Pleckstrin homology and RhoGEF domain containing G1.
      
 0.560
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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