TMEM9 protein (Callithrix jacchus) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

TMEM9

Transmembrane protein 9. (183 aa)

Predicted Functional Partners:

MRI1

0.779

TM9SF2

0.708

PRRX2

0.692

KCNH1

0.687

RBM42

0.617

LOC100394573-2

0.499

GSTT1

0.485

STX1B

0.443

DTD2

0.414

FBXL17

0.400

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DTD2	RBM42	ENSCJAP00000069709	ENSCJAP00000064686	Putative D-tyrosyl-tRNA(Tyr) deacylase 2.	RNA binding motif protein 42.	0.644
DTD2	TMEM9	ENSCJAP00000069709	ENSCJAP00000052697	Putative D-tyrosyl-tRNA(Tyr) deacylase 2.	Transmembrane protein 9.	0.414
FBXL17	TMEM9	ENSCJAP00000029653	ENSCJAP00000052697	F-box and leucine rich repeat protein 17.	Transmembrane protein 9.	0.400
GSTT1	MRI1	ENSCJAP00000051732	ENSCJAP00000066863	Glutathione S-transferase theta-1.	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.528
GSTT1	TMEM9	ENSCJAP00000051732	ENSCJAP00000052697	Glutathione S-transferase theta-1.	Transmembrane protein 9.	0.485
KCNH1	MRI1	ENSCJAP00000062343	ENSCJAP00000066863	Potassium voltage-gated channel subfamily H member 1 isoform 1.	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.690
KCNH1	PRRX2	ENSCJAP00000062343	ENSCJAP00000037737	Potassium voltage-gated channel subfamily H member 1 isoform 1.	Paired related homeobox 2.	0.568
KCNH1	TMEM9	ENSCJAP00000062343	ENSCJAP00000052697	Potassium voltage-gated channel subfamily H member 1 isoform 1.	Transmembrane protein 9.	0.687
LOC100394573-2	MRI1	ENSCJAP00000055623	ENSCJAP00000066863	Histone H3.3.	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.501
LOC100394573-2	PRRX2	ENSCJAP00000055623	ENSCJAP00000037737	Histone H3.3.	Paired related homeobox 2.	0.435
LOC100394573-2	TMEM9	ENSCJAP00000055623	ENSCJAP00000052697	Histone H3.3.	Transmembrane protein 9.	0.499
MRI1	GSTT1	ENSCJAP00000066863	ENSCJAP00000051732	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	Glutathione S-transferase theta-1.	0.528
MRI1	KCNH1	ENSCJAP00000066863	ENSCJAP00000062343	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	Potassium voltage-gated channel subfamily H member 1 isoform 1.	0.690
MRI1	LOC100394573-2	ENSCJAP00000066863	ENSCJAP00000055623	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	Histone H3.3.	0.501
MRI1	PRRX2	ENSCJAP00000066863	ENSCJAP00000037737	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	Paired related homeobox 2.	0.702
MRI1	STX1B	ENSCJAP00000066863	ENSCJAP00000005540	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	Syntaxin 1B; Belongs to the syntaxin family.	0.448
MRI1	TMEM9	ENSCJAP00000066863	ENSCJAP00000052697	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	Transmembrane protein 9.	0.779
PRRX2	KCNH1	ENSCJAP00000037737	ENSCJAP00000062343	Paired related homeobox 2.	Potassium voltage-gated channel subfamily H member 1 isoform 1.	0.568
PRRX2	LOC100394573-2	ENSCJAP00000037737	ENSCJAP00000055623	Paired related homeobox 2.	Histone H3.3.	0.435
PRRX2	MRI1	ENSCJAP00000037737	ENSCJAP00000066863	Paired related homeobox 2.	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.702

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Network Stats

number of nodes:

11

number of edges:

53

average node degree:

9.64

avg. local clustering coefficient:

0.962

expected number of edges:

12

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016491

Oxidoreductase activity

7 of 587

0.74

0.41

0.0498

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:25423265

(2015) Hydroxycinnamic Acid Degradation, a Broadly Conserved Trait, Protects Ralstonia solanacearum from Chemical Plant Defenses and Contributes to Root Colonization and Virulence.

8 of 11

2.53

7.22

1.62e-15

PMID:31392803

(2019) Involvement of a PadR regulator PrhP on virulence of Ralstonia solanacearum by controlling detoxification of phenolic acids and type III secretion system.

3 of 18

1.89

1.09

0.0074

PMID:32283875

(2020) Breast Milk, a Source of Beneficial Microbes and Associated Benefits for Infant Health.

2 of 2

2.67

1.04

0.0129

PMID:23298573

(2013) Characterization and genomic analysis of kraft lignin biodegradation by the beta-proteobacterium Cupriavidus basilensis B-8.

2 of 5

2.27

0.8

0.0339

PMID:17959646

(2007) A comprehensive set of plasmids for vanillate- and xylose-inducible gene expression in Caulobacter crescentus.

2 of 5

2.27

0.8

0.0339

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2543

Mixed, incl. Degradation of aromatic compounds, and Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site

8 of 28

2.12

5.27

4.94e-13

CL:2555

Mixed, incl. Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site, and enoyl-CoA hydratase activity

5 of 5

2.67

4.54

2.33e-09

CL:2205

Mixed, incl. Fatty acid metabolic process, and Valine, leucine and isoleucine degradation

9 of 197

1.33

2.04

4.65e-09

CL:2573

Benzoate degradation

3 of 13

2.03

1.58

0.00080

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

rso01220

Degradation of aromatic compounds

3 of 33

1.63

1.06

0.0060

rso00362

Benzoate degradation

3 of 39

1.55

1.03

0.0060

rso00627

Aminobenzoate degradation

2 of 16

1.76

0.88

0.0187

rso01120

Microbial metabolism in diverse environments

5 of 272

0.93

0.67

0.0062

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