STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOPXHOP homeobox. (90 aa)    
Predicted Functional Partners:
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.764
FAM107A
Family with sequence similarity 107 member A.
      
 0.727
LRIG1
Leucine rich repeats and immunoglobulin like domains 1.
    
 
 0.635
LGR5
Leucine-rich repeat-containing G-protein coupled receptor 5.
   
 
 0.599
PTPRZ1
Protein tyrosine phosphatase receptor type Z1.
      
 0.569
PAX6
Paired box 6.
    
 
 0.559
EVX2
Homeobox domain-containing protein.
      
 0.539
OTP
Homeobox protein orthopedia.
      
 0.530
SFTPC
Pulmonary surfactant-associated protein C isoform 2 proprotein.
      
 0.516
SCGN
Secretagogin, EF-hand calcium binding protein.
    
 
 0.508
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.