node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP2A2 | ATP2B3 | ENSCJAP00000017404 | ENSCJAP00000054916 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.639 |
ATP2A2 | PLN | ENSCJAP00000017404 | ENSCJAP00000070174 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.983 |
ATP2A2 | SLC8A3 | ENSCJAP00000017404 | ENSCJAP00000027319 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.611 |
ATP2B3 | ATP2A2 | ENSCJAP00000054916 | ENSCJAP00000017404 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.639 |
ATP2B3 | KCNJ5 | ENSCJAP00000054916 | ENSCJAP00000016635 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Potassium voltage-gated channel subfamily J member 5. | 0.651 |
ATP2B3 | LOC100408115 | ENSCJAP00000054916 | ENSCJAP00000068606 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.917 |
ATP2B3 | PLN | ENSCJAP00000054916 | ENSCJAP00000070174 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.632 |
ATP2B3 | PRKACA | ENSCJAP00000054916 | ENSCJAP00000061444 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | cAMP-dependent protein kinase catalytic subunit alpha isoform 1; Belongs to the protein kinase superfamily. | 0.917 |
ATP2B3 | PRKACB | ENSCJAP00000054916 | ENSCJAP00000046709 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. | 0.917 |
ATP2B3 | PRKACG | ENSCJAP00000054916 | ENSCJAP00000077508 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.917 |
ATP2B3 | PRKG1 | ENSCJAP00000054916 | ENSCJAP00000054519 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | cGMP-dependent protein kinase. | 0.905 |
ATP2B3 | PRKG2 | ENSCJAP00000054916 | ENSCJAP00000044117 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | cGMP-dependent protein kinase. | 0.905 |
ATP2B3 | SLC8A3 | ENSCJAP00000054916 | ENSCJAP00000027319 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.670 |
KCNJ5 | ATP2B3 | ENSCJAP00000016635 | ENSCJAP00000054916 | Potassium voltage-gated channel subfamily J member 5. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.651 |
KCNJ5 | LOC100408115 | ENSCJAP00000016635 | ENSCJAP00000068606 | Potassium voltage-gated channel subfamily J member 5. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.923 |
KCNJ5 | PRKACA | ENSCJAP00000016635 | ENSCJAP00000061444 | Potassium voltage-gated channel subfamily J member 5. | cAMP-dependent protein kinase catalytic subunit alpha isoform 1; Belongs to the protein kinase superfamily. | 0.923 |
KCNJ5 | PRKACB | ENSCJAP00000016635 | ENSCJAP00000046709 | Potassium voltage-gated channel subfamily J member 5. | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. | 0.923 |
KCNJ5 | PRKACG | ENSCJAP00000016635 | ENSCJAP00000077508 | Potassium voltage-gated channel subfamily J member 5. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.923 |
LOC100408115 | ATP2B3 | ENSCJAP00000068606 | ENSCJAP00000054916 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.917 |
LOC100408115 | KCNJ5 | ENSCJAP00000068606 | ENSCJAP00000016635 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Potassium voltage-gated channel subfamily J member 5. | 0.923 |