node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMDHD1 | APRT | ENSCJAP00000004864 | ENSCJAP00000064568 | Amidohydrolase domain containing 1. | Adenine phosphoribosyltransferase isoform a. | 0.524 |
AMDHD1 | EPHX2 | ENSCJAP00000004864 | ENSCJAP00000036557 | Amidohydrolase domain containing 1. | Bifunctional epoxide hydrolase 2 isoform a. | 0.512 |
AMDHD1 | MRI1 | ENSCJAP00000004864 | ENSCJAP00000066863 | Amidohydrolase domain containing 1. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.424 |
AMDHD1 | MTAP | ENSCJAP00000004864 | ENSCJAP00000055933 | Amidohydrolase domain containing 1. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.606 |
AMDHD1 | NT5E | ENSCJAP00000004864 | ENSCJAP00000047250 | Amidohydrolase domain containing 1. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.731 |
APRT | AMDHD1 | ENSCJAP00000064568 | ENSCJAP00000004864 | Adenine phosphoribosyltransferase isoform a. | Amidohydrolase domain containing 1. | 0.524 |
APRT | GDA | ENSCJAP00000064568 | ENSCJAP00000002529 | Adenine phosphoribosyltransferase isoform a. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.976 |
APRT | MRI1 | ENSCJAP00000064568 | ENSCJAP00000066863 | Adenine phosphoribosyltransferase isoform a. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.480 |
APRT | MTAP | ENSCJAP00000064568 | ENSCJAP00000055933 | Adenine phosphoribosyltransferase isoform a. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.716 |
APRT | NT5E | ENSCJAP00000064568 | ENSCJAP00000047250 | Adenine phosphoribosyltransferase isoform a. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.956 |
BAP1 | MTAP | ENSCJAP00000011709 | ENSCJAP00000055933 | Ubiquitin carboxyl-terminal hydrolase. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.898 |
BAP1 | NF2 | ENSCJAP00000011709 | ENSCJAP00000036954 | Ubiquitin carboxyl-terminal hydrolase. | Merlin isoform 1. | 0.514 |
EPHX2 | AMDHD1 | ENSCJAP00000036557 | ENSCJAP00000004864 | Bifunctional epoxide hydrolase 2 isoform a. | Amidohydrolase domain containing 1. | 0.512 |
EPHX2 | GDA | ENSCJAP00000036557 | ENSCJAP00000002529 | Bifunctional epoxide hydrolase 2 isoform a. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.512 |
EPHX2 | MTAP | ENSCJAP00000036557 | ENSCJAP00000055933 | Bifunctional epoxide hydrolase 2 isoform a. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.822 |
EPHX2 | NT5E | ENSCJAP00000036557 | ENSCJAP00000047250 | Bifunctional epoxide hydrolase 2 isoform a. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.791 |
GDA | APRT | ENSCJAP00000002529 | ENSCJAP00000064568 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Adenine phosphoribosyltransferase isoform a. | 0.976 |
GDA | EPHX2 | ENSCJAP00000002529 | ENSCJAP00000036557 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Bifunctional epoxide hydrolase 2 isoform a. | 0.512 |
GDA | MRI1 | ENSCJAP00000002529 | ENSCJAP00000066863 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.424 |
GDA | MTAP | ENSCJAP00000002529 | ENSCJAP00000055933 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.606 |