node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AADAT | ENSCJAP00000056007 | ENSCJAP00000076078 | ENSCJAP00000056007 | Aminoadipate aminotransferase. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.843 |
AADAT | HMGCL | ENSCJAP00000076078 | ENSCJAP00000038889 | Aminoadipate aminotransferase. | Hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1. | 0.489 |
AADAT | HMGCLL1 | ENSCJAP00000076078 | ENSCJAP00000019980 | Aminoadipate aminotransferase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform b. | 0.489 |
ALDH18A1 | BCKDHA | ENSCJAP00000029812 | ENSCJAP00000037532 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.646 |
ALDH18A1 | BCKDHB | ENSCJAP00000029812 | ENSCJAP00000056525 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.544 |
ALDH18A1 | ENSCJAP00000056007 | ENSCJAP00000029812 | ENSCJAP00000056007 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.848 |
ALDH18A1 | FPGS | ENSCJAP00000029812 | ENSCJAP00000036943 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.693 |
ALDH18A1 | HACL1 | ENSCJAP00000029812 | ENSCJAP00000078657 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. | 0.680 |
ALDH18A1 | HMGCL | ENSCJAP00000029812 | ENSCJAP00000038889 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1. | 0.715 |
ALDH18A1 | HMGCLL1 | ENSCJAP00000029812 | ENSCJAP00000019980 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform b. | 0.715 |
ALDH18A1 | ILVBL | ENSCJAP00000029812 | ENSCJAP00000077881 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | IlvB acetolactate synthase like; Belongs to the TPP enzyme family. | 0.680 |
BCKDHA | ALDH18A1 | ENSCJAP00000037532 | ENSCJAP00000029812 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.646 |
BCKDHA | BCKDHB | ENSCJAP00000037532 | ENSCJAP00000056525 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Branched chain keto acid dehydrogenase E1 subunit beta. | 0.999 |
BCKDHA | ENSCJAP00000056007 | ENSCJAP00000037532 | ENSCJAP00000056007 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.851 |
BCKDHA | HACL1 | ENSCJAP00000037532 | ENSCJAP00000078657 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. | 0.858 |
BCKDHA | HMGCL | ENSCJAP00000037532 | ENSCJAP00000038889 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1. | 0.578 |
BCKDHA | HMGCLL1 | ENSCJAP00000037532 | ENSCJAP00000019980 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform b. | 0.578 |
BCKDHA | ILVBL | ENSCJAP00000037532 | ENSCJAP00000077881 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | IlvB acetolactate synthase like; Belongs to the TPP enzyme family. | 0.858 |
BCKDHB | ALDH18A1 | ENSCJAP00000056525 | ENSCJAP00000029812 | Branched chain keto acid dehydrogenase E1 subunit beta. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.544 |
BCKDHB | BCKDHA | ENSCJAP00000056525 | ENSCJAP00000037532 | Branched chain keto acid dehydrogenase E1 subunit beta. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |