node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRG2 | CFTR | ENSCJAP00000010375 | ENSCJAP00000009011 | Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.495 |
ADGRG2 | SLC26A9 | ENSCJAP00000010375 | ENSCJAP00000056319 | Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.557 |
CFTR | ADGRG2 | ENSCJAP00000009011 | ENSCJAP00000010375 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. | 0.495 |
CFTR | KCNN4 | ENSCJAP00000009011 | ENSCJAP00000024637 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Potassium calcium-activated channel subfamily N member 4. | 0.506 |
CFTR | SLC26A9 | ENSCJAP00000009011 | ENSCJAP00000056319 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.581 |
KCNN4 | CFTR | ENSCJAP00000024637 | ENSCJAP00000009011 | Potassium calcium-activated channel subfamily N member 4. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.506 |
KCNN4 | SLC26A9 | ENSCJAP00000024637 | ENSCJAP00000056319 | Potassium calcium-activated channel subfamily N member 4. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.472 |
MRE11 | SLC26A9 | ENSCJAP00000007368 | ENSCJAP00000056319 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.480 |
SLC26A9 | ADGRG2 | ENSCJAP00000056319 | ENSCJAP00000010375 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. | 0.557 |
SLC26A9 | CFTR | ENSCJAP00000056319 | ENSCJAP00000009011 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.581 |
SLC26A9 | KCNN4 | ENSCJAP00000056319 | ENSCJAP00000024637 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Potassium calcium-activated channel subfamily N member 4. | 0.472 |
SLC26A9 | MRE11 | ENSCJAP00000056319 | ENSCJAP00000007368 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.480 |
SLC26A9 | SLC38A3 | ENSCJAP00000056319 | ENSCJAP00000074817 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Solute carrier family 38 member 3. | 0.580 |
SLC26A9 | SLC4A1 | ENSCJAP00000056319 | ENSCJAP00000018482 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Anion exchange protein. | 0.434 |
SLC26A9 | SLC4A3 | ENSCJAP00000056319 | ENSCJAP00000018486 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Anion exchange protein. | 0.540 |
SLC26A9 | SLC4A9 | ENSCJAP00000056319 | ENSCJAP00000030907 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Anion exchange protein. | 0.640 |
SLC26A9 | TRPA1 | ENSCJAP00000056319 | ENSCJAP00000014378 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. | 0.477 |
SLC38A3 | SLC26A9 | ENSCJAP00000074817 | ENSCJAP00000056319 | Solute carrier family 38 member 3. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.580 |
SLC38A3 | SLC4A9 | ENSCJAP00000074817 | ENSCJAP00000030907 | Solute carrier family 38 member 3. | Anion exchange protein. | 0.620 |
SLC4A1 | SLC26A9 | ENSCJAP00000018482 | ENSCJAP00000056319 | Anion exchange protein. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.434 |