STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTCH1Protein patched homolog 1 isoform L. (1449 aa)    
Predicted Functional Partners:
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.999
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.998
CDON
Cell adhesion associated, oncogene regulated.
    
 0.996
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.996
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.993
GAS1
Growth arrest specific 1.
     
 0.990
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.986
SMURF1
E3 ubiquitin-protein ligase.
    
 0.978
SMURF2
E3 ubiquitin-protein ligase.
    
 0.978
LRP2
LDL receptor related protein 2.
   
 
 0.930
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.