STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (746 aa)    
Predicted Functional Partners:
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17 preproprotein.
     
0.944
NCSTN
Nicastrin.
    
 
 0.874
TSPAN33
Tetraspanin.
    
 0.871
BACE1
Beta-secretase 1 isoform A preproprotein; Belongs to the peptidase A1 family.
    
 
 0.812
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 
 0.770
TSPAN14
Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family.
   
 0.747
APP
Amyloid beta A4 protein isoform a.
    
 0.739
NOTCH1
Notch receptor 1.
    
 0.734
TSPAN5
Tetraspanin.
   
 0.724
PSENEN
Presenilin enhancer, gamma-secretase subunit.
    
 
 0.722
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.