ENSCJAP00000063591 protein (Callithrix jacchus)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

ENSCJAP00000063591

CobW C-terminal domain-containing protein. (461 aa)

Predicted Functional Partners:

METAP1

0.641

MRPL33

0.639

RPS29

0.508

F7D3Q9_CALJA

0.503

ENSCJAP00000077476

0.503

ENSCJAP00000077517

0.503

RPS29-2

0.503

RSAD1

0.502

F6Y2W4_CALJA

0.501

MRPS14

0.501

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCJAP00000063591	ENSCJAP00000077476	ENSCJAP00000063591	ENSCJAP00000077476	CobW C-terminal domain-containing protein.	Uncharacterized protein.	0.503
ENSCJAP00000063591	ENSCJAP00000077517	ENSCJAP00000063591	ENSCJAP00000077517	CobW C-terminal domain-containing protein.	Uncharacterized protein.	0.503
ENSCJAP00000063591	F6Y2W4_CALJA	ENSCJAP00000063591	ENSCJAP00000016436	CobW C-terminal domain-containing protein.	Uncharacterized protein.	0.501
ENSCJAP00000063591	F7D3Q9_CALJA	ENSCJAP00000063591	ENSCJAP00000032021	CobW C-terminal domain-containing protein.	Uncharacterized protein.	0.503
ENSCJAP00000063591	METAP1	ENSCJAP00000063591	ENSCJAP00000013373	CobW C-terminal domain-containing protein.	Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	0.641
ENSCJAP00000063591	MRPL33	ENSCJAP00000063591	ENSCJAP00000058214	CobW C-terminal domain-containing protein.	39S ribosomal protein L33, mitochondrial isoform a.	0.639
ENSCJAP00000063591	MRPS14	ENSCJAP00000063591	ENSCJAP00000052259	CobW C-terminal domain-containing protein.	Uncharacterized protein.	0.501
ENSCJAP00000063591	RPS29	ENSCJAP00000063591	ENSCJAP00000063985	CobW C-terminal domain-containing protein.	Ribosomal protein S29.	0.508
ENSCJAP00000063591	RPS29-2	ENSCJAP00000063591	ENSCJAP00000078096	CobW C-terminal domain-containing protein.	Ribosomal protein S29.	0.503
ENSCJAP00000063591	RSAD1	ENSCJAP00000063591	ENSCJAP00000034901	CobW C-terminal domain-containing protein.	Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family.	0.502
ENSCJAP00000077476	ENSCJAP00000063591	ENSCJAP00000077476	ENSCJAP00000063591	Uncharacterized protein.	CobW C-terminal domain-containing protein.	0.503
ENSCJAP00000077476	METAP1	ENSCJAP00000077476	ENSCJAP00000013373	Uncharacterized protein.	Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	0.624
ENSCJAP00000077476	MRPL33	ENSCJAP00000077476	ENSCJAP00000058214	Uncharacterized protein.	39S ribosomal protein L33, mitochondrial isoform a.	0.882
ENSCJAP00000077517	ENSCJAP00000063591	ENSCJAP00000077517	ENSCJAP00000063591	Uncharacterized protein.	CobW C-terminal domain-containing protein.	0.503
ENSCJAP00000077517	METAP1	ENSCJAP00000077517	ENSCJAP00000013373	Uncharacterized protein.	Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	0.624
ENSCJAP00000077517	MRPL33	ENSCJAP00000077517	ENSCJAP00000058214	Uncharacterized protein.	39S ribosomal protein L33, mitochondrial isoform a.	0.882
F6Y2W4_CALJA	ENSCJAP00000063591	ENSCJAP00000016436	ENSCJAP00000063591	Uncharacterized protein.	CobW C-terminal domain-containing protein.	0.501
F6Y2W4_CALJA	METAP1	ENSCJAP00000016436	ENSCJAP00000013373	Uncharacterized protein.	Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	0.615
F6Y2W4_CALJA	MRPL33	ENSCJAP00000016436	ENSCJAP00000058214	Uncharacterized protein.	39S ribosomal protein L33, mitochondrial isoform a.	0.940
F7D3Q9_CALJA	ENSCJAP00000063591	ENSCJAP00000032021	ENSCJAP00000063591	Uncharacterized protein.	CobW C-terminal domain-containing protein.	0.503

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

38

average node degree:

6.91

avg. local clustering coefficient:

0.966

expected number of edges:

33

PPI enrichment p-value:

0.24

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

8 of 104

1.18

1.4

2.81e-06

GO:0019538

Protein metabolic process

10 of 228

0.93

1.0

2.09e-06

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 254

0.84

0.81

2.41e-05

GO:1901566

Organonitrogen compound biosynthetic process

9 of 276

0.8

0.75

4.42e-05

GO:1901564

Organonitrogen compound metabolic process

11 of 473

0.66

0.61

8.82e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

7 of 53

1.41

1.88

1.33e-06

GO:0019843

rRNA binding

4 of 41

1.28

0.86

0.0080

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

7 of 55

1.4

1.96

3.12e-07

GO:0044391

Ribosomal subunit

2 of 15

1.42

0.64

0.0470

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:106

Structural constituent of ribosome

7 of 54

1.4

2.01

1.74e-07

CL:103

Structural constituent of ribosome, and Elongation factor

8 of 68

1.36

1.99

5.59e-08

CL:85

Mixed, incl. Translation, and Oxidative phosphorylation

10 of 168

1.07

1.33

5.27e-08

CL:146

Ribosomal protein

3 of 17

1.54

1.13

0.0031

CL:108

Structural constituent of ribosome

4 of 42

1.27

1.05

0.0016

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

7 of 54

1.4

1.97

3.20e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 42

1.51

2.28

1.22e-07

GOCC:0044391

Ribosomal subunit

5 of 22

1.65

2.05

9.09e-06

GOCC:0022626

Cytosolic ribosome

4 of 16

1.69

1.85

5.67e-05

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 10

1.77

1.5

0.00070

GOCC:0015934

Large ribosomal subunit

2 of 10

1.59

0.77

0.0277

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

7 of 53

1.41

1.96

4.58e-07

KW-0699

rRNA-binding

4 of 39

1.3

1.03

0.0023

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