ENSCJAP00000065499 protein (Callithrix jacchus)

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Score

ENSCJAP00000065499

Uncharacterized protein. (77 aa)

Predicted Functional Partners:

USP7

0.749

DAXX

0.647

ATM

0.617

SCP2

0.600

UBC

0.594

ENSCJAP00000059313

0.594

AR

0.580

TP63

0.579

TP73

0.579

RPL11

0.569

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	DAXX	ENSCJAP00000006494	ENSCJAP00000040372	Androgen receptor.	Death domain-associated protein 6 isoform a.	0.461
AR	ENSCJAP00000065499	ENSCJAP00000006494	ENSCJAP00000065499	Androgen receptor.	Uncharacterized protein.	0.580
ATM	DAXX	ENSCJAP00000018844	ENSCJAP00000040372	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Death domain-associated protein 6 isoform a.	0.499
ATM	ENSCJAP00000059313	ENSCJAP00000018844	ENSCJAP00000059313	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.623
ATM	ENSCJAP00000065499	ENSCJAP00000018844	ENSCJAP00000065499	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.617
ATM	TP63	ENSCJAP00000018844	ENSCJAP00000052660	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.846
ATM	TP73	ENSCJAP00000018844	ENSCJAP00000058778	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.	0.831
ATM	UBC	ENSCJAP00000018844	ENSCJAP00000057758	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.609
ATM	USP7	ENSCJAP00000018844	ENSCJAP00000071394	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.452
DAXX	AR	ENSCJAP00000040372	ENSCJAP00000006494	Death domain-associated protein 6 isoform a.	Androgen receptor.	0.461
DAXX	ATM	ENSCJAP00000040372	ENSCJAP00000018844	Death domain-associated protein 6 isoform a.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.499
DAXX	ENSCJAP00000059313	ENSCJAP00000040372	ENSCJAP00000059313	Death domain-associated protein 6 isoform a.	Uncharacterized protein.	0.443
DAXX	ENSCJAP00000065499	ENSCJAP00000040372	ENSCJAP00000065499	Death domain-associated protein 6 isoform a.	Uncharacterized protein.	0.647
DAXX	UBC	ENSCJAP00000040372	ENSCJAP00000057758	Death domain-associated protein 6 isoform a.	Uncharacterized protein.	0.443
DAXX	USP7	ENSCJAP00000040372	ENSCJAP00000071394	Death domain-associated protein 6 isoform a.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.954
ENSCJAP00000059313	ATM	ENSCJAP00000059313	ENSCJAP00000018844	Uncharacterized protein.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.623
ENSCJAP00000059313	DAXX	ENSCJAP00000059313	ENSCJAP00000040372	Uncharacterized protein.	Death domain-associated protein 6 isoform a.	0.443
ENSCJAP00000059313	ENSCJAP00000065499	ENSCJAP00000059313	ENSCJAP00000065499	Uncharacterized protein.	Uncharacterized protein.	0.594
ENSCJAP00000059313	RPL11	ENSCJAP00000059313	ENSCJAP00000038979	Uncharacterized protein.	60S ribosomal protein L11 isoform 1; Belongs to the universal ribosomal protein uL5 family.	0.741
ENSCJAP00000059313	SCP2	ENSCJAP00000059313	ENSCJAP00000050259	Uncharacterized protein.	Non-specific lipid-transfer protein isoform 1 proprotein; Belongs to the thiolase-like superfamily. Thiolase family.	0.675