node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYP1A1 | CYP2B6 | ENSCJAP00000032652 | ENSCJAP00000037334 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | 0.445 |
CYP1A1 | CYP3A21 | ENSCJAP00000032652 | ENSCJAP00000047441 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.961 |
CYP1A1 | NR1I3 | ENSCJAP00000032652 | ENSCJAP00000066054 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Nuclear receptor subfamily 1 group I member 3. | 0.628 |
CYP2B6 | CYP1A1 | ENSCJAP00000037334 | ENSCJAP00000032652 | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.445 |
CYP2B6 | CYP3A21 | ENSCJAP00000037334 | ENSCJAP00000047441 | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.589 |
CYP2B6 | NR1I3 | ENSCJAP00000037334 | ENSCJAP00000066054 | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | Nuclear receptor subfamily 1 group I member 3. | 0.707 |
CYP3A21 | CYP1A1 | ENSCJAP00000047441 | ENSCJAP00000032652 | Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.961 |
CYP3A21 | CYP2B6 | ENSCJAP00000047441 | ENSCJAP00000037334 | Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. | 0.589 |
CYP3A21 | MED1 | ENSCJAP00000047441 | ENSCJAP00000015874 | Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.659 |
CYP3A21 | NR1I3 | ENSCJAP00000047441 | ENSCJAP00000066054 | Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Nuclear receptor subfamily 1 group I member 3. | 0.604 |
MED1 | CYP3A21 | ENSCJAP00000015874 | ENSCJAP00000047441 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.659 |
MED1 | NCOA1 | ENSCJAP00000015874 | ENSCJAP00000014783 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.793 |
MED1 | NCOA2 | ENSCJAP00000015874 | ENSCJAP00000074903 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.664 |
MED1 | NCOA3 | ENSCJAP00000015874 | ENSCJAP00000071560 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.969 |
MED1 | NR1I3 | ENSCJAP00000015874 | ENSCJAP00000066054 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group I member 3. | 0.722 |
MED1 | RXRA | ENSCJAP00000015874 | ENSCJAP00000053089 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor alpha. | 0.971 |
MED1 | RXRB | ENSCJAP00000015874 | ENSCJAP00000040245 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor beta. | 0.924 |
MED1 | RXRG | ENSCJAP00000015874 | ENSCJAP00000008496 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoic acid receptor RXR-gamma isoform a. | 0.935 |
NCOA1 | MED1 | ENSCJAP00000014783 | ENSCJAP00000015874 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.793 |
NCOA1 | NCOA2 | ENSCJAP00000014783 | ENSCJAP00000074903 | Nuclear receptor coactivator. | Nuclear receptor coactivator. | 0.993 |