NEDD4L protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NEDD4L

NEDD4 like E3 ubiquitin protein ligase. (1254 aa)

Predicted Functional Partners:

SGK1

0.992

SCNN1B

0.990

SCNN1A

0.985

SMAD3

0.977

SMAD7

0.960

AMOT

0.947

NEDD4

0.930

SFN

0.927

SMAD2

0.882

ENSCJAP00000059313

0.875

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMOT	NEDD4	ENSCJAP00000013045	ENSCJAP00000066364	Angiomotin.	NEDD4 E3 ubiquitin protein ligase.	0.713
AMOT	NEDD4L	ENSCJAP00000013045	ENSCJAP00000066326	Angiomotin.	NEDD4 like E3 ubiquitin protein ligase.	0.947
AMOT	SFN	ENSCJAP00000013045	ENSCJAP00000065969	Angiomotin.	Stratifin; Belongs to the 14-3-3 family.	0.831
ENSCJAP00000059313	NEDD4	ENSCJAP00000059313	ENSCJAP00000066364	Uncharacterized protein.	NEDD4 E3 ubiquitin protein ligase.	0.878
ENSCJAP00000059313	NEDD4L	ENSCJAP00000059313	ENSCJAP00000066326	Uncharacterized protein.	NEDD4 like E3 ubiquitin protein ligase.	0.875
ENSCJAP00000059313	SMAD7	ENSCJAP00000059313	ENSCJAP00000062049	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.448
NEDD4	AMOT	ENSCJAP00000066364	ENSCJAP00000013045	NEDD4 E3 ubiquitin protein ligase.	Angiomotin.	0.713
NEDD4	ENSCJAP00000059313	ENSCJAP00000066364	ENSCJAP00000059313	NEDD4 E3 ubiquitin protein ligase.	Uncharacterized protein.	0.878
NEDD4	NEDD4L	ENSCJAP00000066364	ENSCJAP00000066326	NEDD4 E3 ubiquitin protein ligase.	NEDD4 like E3 ubiquitin protein ligase.	0.930
NEDD4	SCNN1A	ENSCJAP00000066364	ENSCJAP00000001205	NEDD4 E3 ubiquitin protein ligase.	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.823
NEDD4	SCNN1B	ENSCJAP00000066364	ENSCJAP00000038280	NEDD4 E3 ubiquitin protein ligase.	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.954
NEDD4	SGK1	ENSCJAP00000066364	ENSCJAP00000005050	NEDD4 E3 ubiquitin protein ligase.	Non-specific serine/threonine protein kinase.	0.717
NEDD4	SMAD2	ENSCJAP00000066364	ENSCJAP00000008504	NEDD4 E3 ubiquitin protein ligase.	Mothers against decapentaplegic homolog.	0.717
NEDD4	SMAD3	ENSCJAP00000066364	ENSCJAP00000003797	NEDD4 E3 ubiquitin protein ligase.	Mothers against decapentaplegic homolog.	0.721
NEDD4	SMAD7	ENSCJAP00000066364	ENSCJAP00000062049	NEDD4 E3 ubiquitin protein ligase.	Mothers against decapentaplegic homolog.	0.845
NEDD4L	AMOT	ENSCJAP00000066326	ENSCJAP00000013045	NEDD4 like E3 ubiquitin protein ligase.	Angiomotin.	0.947
NEDD4L	ENSCJAP00000059313	ENSCJAP00000066326	ENSCJAP00000059313	NEDD4 like E3 ubiquitin protein ligase.	Uncharacterized protein.	0.875
NEDD4L	NEDD4	ENSCJAP00000066326	ENSCJAP00000066364	NEDD4 like E3 ubiquitin protein ligase.	NEDD4 E3 ubiquitin protein ligase.	0.930
NEDD4L	SCNN1A	ENSCJAP00000066326	ENSCJAP00000001205	NEDD4 like E3 ubiquitin protein ligase.	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.985
NEDD4L	SCNN1B	ENSCJAP00000066326	ENSCJAP00000038280	NEDD4 like E3 ubiquitin protein ligase.	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.990