STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCJAP00000068076Pyrin domain-containing protein. (98 aa)    
Predicted Functional Partners:
ENSCJAP00000073487
Uncharacterized protein.
   
 0.675
RALB
Ras-related protein Ral-B.
     
 0.570
BRAT1
BRCA1 associated ATM activator 1.
      
 0.562
NLRP1
NLR family pyrin domain containing 1.
    
 
 0.522
NLRP6
NLR family pyrin domain containing 6.
 
    
 0.516
NLRP12
NLR family pyrin domain containing 12.
      
 0.515
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.485
NLRP3
NLR family pyrin domain containing 3.
 
    
 0.473
TXNIP
Thioredoxin interacting protein.
     
 0.456
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
     
 0.439
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.