STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2129 aa)    
Predicted Functional Partners:
FIG4
FIG4 phosphoinositide 5-phosphatase.
    
 0.999
VAC14
VAC14 component of PIKFYVE complex.
    
 0.981
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.973
PI4KB
Phosphatidylinositol 4-kinase beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation (By similarity). Involved in Golgi-to-plasma membrane trafficking (By similarity).
     
 0.955
PI4KA
Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.
     
 0.952
DIPK2A
Divergent protein kinase domain 2A.
    
 0.948
PIP4K2C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform a.
     
0.942
MTMR7
Myotubularin-related protein 7.
     
 0.935
PI4K2B
Phosphatidylinositol 4-kinase type 2 beta.
     
 0.933
PI4K2A
Phosphatidylinositol 4-kinase type 2-alpha.
     
 0.933
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.