STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSG2Desmoglein-2 preproprotein. (1117 aa)    
Predicted Functional Partners:
DSC1
Desmocollin-2 isoform Dsc2a preproprotein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
0.991
PKP2
Plakophilin-2 isoform 2a.
   
 0.976
DSP
Desmoplakin.
   
 0.961
JUP
Junction plakoglobin.
    
 0.948
PKP1
Plakophilin 1.
   
 0.763
PKP3
Plakophilin 3.
   
 0.691
TMEM43
Transmembrane protein 43.
      
 0.689
CTNNB1
Catenin beta 1.
    
 0.615
CASS4
Cas scaffold protein family member 4.
    
 0.594
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.592
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (24%) [HD]