ENSCJAP00000073648 protein (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSCJAP00000073648

Uncharacterized protein. (325 aa)

Predicted Functional Partners:

SRSF2

0.701

SRSF8

0.658

HNRNPK

0.612

ENSCJAP00000053202

0.598

HNRNPA2B1

0.572

HNRNPU

0.546

SRSF6

0.539

SRSF11

0.538

FAU

0.528

ENSCJAP00000077762

0.528

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCJAP00000053202	ENSCJAP00000073648	ENSCJAP00000053202	ENSCJAP00000073648	RRM domain-containing protein.	Uncharacterized protein.	0.598
ENSCJAP00000053202	ENSCJAP00000077762	ENSCJAP00000053202	ENSCJAP00000077762	RRM domain-containing protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.528
ENSCJAP00000053202	FAU	ENSCJAP00000053202	ENSCJAP00000004437	RRM domain-containing protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.528
ENSCJAP00000053202	HNRNPA2B1	ENSCJAP00000053202	ENSCJAP00000014695	RRM domain-containing protein.	Heterogeneous nuclear ribonucleoproteins A2/B1 isoform B1.	0.657
ENSCJAP00000053202	HNRNPK	ENSCJAP00000053202	ENSCJAP00000046691	RRM domain-containing protein.	Heterogeneous nuclear ribonucleoprotein K isoform a.	0.698
ENSCJAP00000053202	HNRNPU	ENSCJAP00000053202	ENSCJAP00000031301	RRM domain-containing protein.	Heterogeneous nuclear ribonucleoprotein U isoform a.	0.435
ENSCJAP00000053202	SRSF11	ENSCJAP00000053202	ENSCJAP00000032737	RRM domain-containing protein.	Serine and arginine rich splicing factor 11.	0.703
ENSCJAP00000053202	SRSF2	ENSCJAP00000053202	ENSCJAP00000024666	RRM domain-containing protein.	Serine and arginine rich splicing factor 2.	0.756
ENSCJAP00000053202	SRSF6	ENSCJAP00000053202	ENSCJAP00000059311	RRM domain-containing protein.	Serine/arginine-rich splicing factor 6.	0.787
ENSCJAP00000053202	SRSF8	ENSCJAP00000053202	ENSCJAP00000075254	RRM domain-containing protein.	Serine and arginine rich splicing factor 8.	0.762
ENSCJAP00000073648	ENSCJAP00000053202	ENSCJAP00000073648	ENSCJAP00000053202	Uncharacterized protein.	RRM domain-containing protein.	0.598
ENSCJAP00000073648	ENSCJAP00000077762	ENSCJAP00000073648	ENSCJAP00000077762	Uncharacterized protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.528
ENSCJAP00000073648	FAU	ENSCJAP00000073648	ENSCJAP00000004437	Uncharacterized protein.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.528
ENSCJAP00000073648	HNRNPA2B1	ENSCJAP00000073648	ENSCJAP00000014695	Uncharacterized protein.	Heterogeneous nuclear ribonucleoproteins A2/B1 isoform B1.	0.572
ENSCJAP00000073648	HNRNPK	ENSCJAP00000073648	ENSCJAP00000046691	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein K isoform a.	0.612
ENSCJAP00000073648	HNRNPU	ENSCJAP00000073648	ENSCJAP00000031301	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein U isoform a.	0.546
ENSCJAP00000073648	SRSF11	ENSCJAP00000073648	ENSCJAP00000032737	Uncharacterized protein.	Serine and arginine rich splicing factor 11.	0.538
ENSCJAP00000073648	SRSF2	ENSCJAP00000073648	ENSCJAP00000024666	Uncharacterized protein.	Serine and arginine rich splicing factor 2.	0.701
ENSCJAP00000073648	SRSF6	ENSCJAP00000073648	ENSCJAP00000059311	Uncharacterized protein.	Serine/arginine-rich splicing factor 6.	0.539
ENSCJAP00000073648	SRSF8	ENSCJAP00000073648	ENSCJAP00000075254	Uncharacterized protein.	Serine and arginine rich splicing factor 8.	0.658

page 1 of 5

Network Stats

number of nodes:

10

number of edges:

9

average node degree:

1.8

avg. local clustering coefficient:

0.9

expected number of edges:

9

PPI enrichment p-value:

0.549

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009082

Branched-chain amino acid biosynthetic process

7 of 17

1.89

3.48

3.32e-09

GO:0009099

Valine biosynthetic process

5 of 8

2.07

2.97

5.78e-07

GO:0009097

Isoleucine biosynthetic process

5 of 10

1.97

2.83

6.93e-07

GO:1901607

Alpha-amino acid biosynthetic process

7 of 59

1.35

1.79

8.69e-07

GO:1901605

Alpha-amino acid metabolic process

8 of 85

1.25

1.62

5.78e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003984

Acetolactate synthase activity

3 of 5

2.05

1.3

0.0032

GO:1990610

Acetolactate synthase regulator activity

2 of 2

2.27

0.85

0.0268

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:844

Valine, leucine and isoleucine biosynthesis, and Phosphopantetheine

9 of 20

1.93

4.8

1.32e-13

CL:845

Valine, leucine and isoleucine biosynthesis

8 of 15

2.0

4.76

1.48e-12

CL:846

Valine metabolic process

7 of 10

2.12

4.73

1.83e-11

CL:848

Valine metabolic process

3 of 5

2.05

1.83

0.00024

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00290

Valine, leucine and isoleucine biosynthesis

8 of 15

2.0

4.82

9.46e-13

map01210

2-Oxocarboxylic acid metabolism

7 of 22

1.78

3.39

7.67e-10

map00770

Pantothenate and CoA biosynthesis

5 of 19

1.7

2.35

1.49e-06

map00660

C5-Branched dibasic acid metabolism

4 of 10

1.88

2.35

7.07e-06

map01230

Biosynthesis of amino acids

8 of 94

1.2

1.6

1.27e-07

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005948

Acetolactate synthase complex

3 of 5

2.05

1.49

0.0013

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0100

Branched-chain amino acid biosynthesis

4 of 10

1.88

1.97

6.75e-05

KW-0432

Leucine biosynthesis

2 of 5

1.88

0.81

0.0287

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13710

ACT domain

2 of 2

2.27

0.72

0.0483

PF10369

Small subunit of acetolactate synthase

2 of 2

2.27

0.72

0.0483

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About