STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALX3ALX homeobox 3. (462 aa)    
Predicted Functional Partners:
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
      
 0.770
LHX4
LIM homeobox 4.
   
0.725
LHX3
Uncharacterized protein.
   
0.725
ASIP
Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
      
 0.689
LDB1
LIM domain binding 1.
    
 0.668
LDB2
LIM domain-binding protein 2 isoform a.
    
 0.668
NCKAP1
NCK associated protein 1.
      
 0.625
SEMA6B
Semaphorin-6B; Belongs to the semaphorin family.
      
 0.618
MITF
Microphthalmia-associated transcription factor isoform 1.
      
 0.597
TBX15
T-box transcription factor 15.
    
 
 0.592
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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