NFE2L2 protein (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NFE2L2

Nuclear factor, erythroid 2 like 2. (622 aa)

Predicted Functional Partners:

KEAP1

0.999

MAFG

0.954

DDIT3

0.936

EIF2AK3

0.936

ENSCJAP00000059748

0.936

EIF2AK2

0.922

KLHL17

0.922

MAPK7

0.917

PARK7

0.916

EIF2AK4

0.909

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDIT3	ENSCJAP00000059748	ENSCJAP00000043609	ENSCJAP00000059748	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.900
DDIT3	NFE2L2	ENSCJAP00000043609	ENSCJAP00000078532	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Nuclear factor, erythroid 2 like 2.	0.936
EIF2AK2	EIF2AK4	ENSCJAP00000006979	ENSCJAP00000038930	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2-alpha kinase 4.	0.447
EIF2AK2	NFE2L2	ENSCJAP00000006979	ENSCJAP00000078532	Eukaryotic translation initiation factor 2 alpha kinase 2.	Nuclear factor, erythroid 2 like 2.	0.922
EIF2AK3	EIF2AK4	ENSCJAP00000050396	ENSCJAP00000038930	Eukaryotic translation initiation factor 2-alpha kinase 3.	Eukaryotic translation initiation factor 2-alpha kinase 4.	0.554
EIF2AK3	NFE2L2	ENSCJAP00000050396	ENSCJAP00000078532	Eukaryotic translation initiation factor 2-alpha kinase 3.	Nuclear factor, erythroid 2 like 2.	0.936
EIF2AK4	EIF2AK2	ENSCJAP00000038930	ENSCJAP00000006979	Eukaryotic translation initiation factor 2-alpha kinase 4.	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.447
EIF2AK4	EIF2AK3	ENSCJAP00000038930	ENSCJAP00000050396	Eukaryotic translation initiation factor 2-alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.554
EIF2AK4	NFE2L2	ENSCJAP00000038930	ENSCJAP00000078532	Eukaryotic translation initiation factor 2-alpha kinase 4.	Nuclear factor, erythroid 2 like 2.	0.909
ENSCJAP00000059748	DDIT3	ENSCJAP00000059748	ENSCJAP00000043609	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.900
ENSCJAP00000059748	NFE2L2	ENSCJAP00000059748	ENSCJAP00000078532	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Nuclear factor, erythroid 2 like 2.	0.936
KEAP1	MAFG	ENSCJAP00000012371	ENSCJAP00000033816	Kelch-like ECH-associated protein 1.	MAF bZIP transcription factor G.	0.441
KEAP1	NFE2L2	ENSCJAP00000012371	ENSCJAP00000078532	Kelch-like ECH-associated protein 1.	Nuclear factor, erythroid 2 like 2.	0.999
KLHL17	NFE2L2	ENSCJAP00000073773	ENSCJAP00000078532	BTB domain-containing protein.	Nuclear factor, erythroid 2 like 2.	0.922
MAFG	KEAP1	ENSCJAP00000033816	ENSCJAP00000012371	MAF bZIP transcription factor G.	Kelch-like ECH-associated protein 1.	0.441
MAFG	NFE2L2	ENSCJAP00000033816	ENSCJAP00000078532	MAF bZIP transcription factor G.	Nuclear factor, erythroid 2 like 2.	0.954
MAPK7	NFE2L2	ENSCJAP00000002248	ENSCJAP00000078532	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Nuclear factor, erythroid 2 like 2.	0.917
NFE2L2	DDIT3	ENSCJAP00000078532	ENSCJAP00000043609	Nuclear factor, erythroid 2 like 2.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.936
NFE2L2	EIF2AK2	ENSCJAP00000078532	ENSCJAP00000006979	Nuclear factor, erythroid 2 like 2.	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.922
NFE2L2	EIF2AK3	ENSCJAP00000078532	ENSCJAP00000050396	Nuclear factor, erythroid 2 like 2.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.936