STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SDP33529.1Putative DeoR family transcriptional regulator, stage III sporulation protein D. (83 aa)    
Predicted Functional Partners:
SDO85505.1
Stage III sporulation protein AE.
  
    0.958
SDP51193.1
Transcriptional regulator, AbrB family.
  
  
 0.904
SDP27170.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.900
SDP81813.1
Stage II sporulation protein R.
  
   
 0.900
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.897
SDO86053.1
Two-component system, response regulator, stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.895
SDP51393.1
Stage II sporulation protein E.
  
   
 0.882
SDO85378.1
Stage III sporulation protein AA.
  
   
 0.880
SDP58033.1
Stage II sporulation protein P.
  
  
 0.874
SDP33480.1
Stage II sporulation protein D.
 
   
 0.868
Your Current Organism:
Clostridium gasigenes
NCBI taxonomy Id: 94869
Other names: ATCC BAA-158, C. gasigenes, CIP 106517, Clostridium gasigenes Broda et al. 2000, DSM 12272, strain DB1A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.