STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDP71012.1CBS domain-containing protein. (136 aa)    
Predicted Functional Partners:
SDP69088.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
  0.943
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.937
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.887
SDO85630.1
Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family.
   
    0.828
SDP86436.1
Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.665
SDO73830.1
Diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.640
SDO95342.1
CBS domain-containing protein.
 
  
  0.637
SDP24827.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.588
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.523
gpmI
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.508
Your Current Organism:
Clostridium gasigenes
NCBI taxonomy Id: 94869
Other names: ATCC BAA-158, C. gasigenes, CIP 106517, Clostridium gasigenes Broda et al. 2000, DSM 12272, strain DB1A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.