Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ASMTAcetylserotonin O-methyltransferase. (440 aa)    
Predicted Functional Partners:
AANAT
Aralkylamine N-acetyltransferase.
     
 0.979
ALDH3A2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.847
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]
      
 0.847
ALDH9A1
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
     
 0.847
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 
 0.841
CYP1A1
Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 
 0.841
IDO1
Indoleamine 2,3-dioxygenase 1.
     
 0.839
IDO2
Indoleamine 2,3-dioxygenase 2.
     
 0.836
ALDH1B1
Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family.
     
 0.833
ALDH2
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
     
 0.833
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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