Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CLCN6Chloride voltage-gated channel 6; Belongs to the chloride channel (TC 2.A.49) family. (930 aa)    
Predicted Functional Partners:
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
    
 0.960
MED19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.775
OCRL
OCRL inositol polyphosphate-5-phosphatase.
   
  
 0.768
PRPF3
Pre-mRNA processing factor 3.
      
 0.763
CHRNG
Cholinergic receptor nicotinic gamma subunit.
      
 0.751
OGDHL
Oxoglutarate dehydrogenase like.
      
 0.624
CLN5
Uncharacterized protein.
      
 0.624
FAM131B
Family with sequence similarity 131 member B.
     
 0.614
RAPGEF5
Rap guanine nucleotide exchange factor 5.
      
 0.559
LOC108316220
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
  
 0.554
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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