close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGMS1Sphingomyelin synthase 1. (419 aa)    
Predicted Functional Partners:
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
     
 0.971
CERK
Ceramide kinase.
     
 0.970
ASAH2
Neutral ceramidase.
 
   
 0.962
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.961
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.961
CERS3
Ceramide synthase 3.
     
 0.960
CERS2
Ceramide synthase 2.
     
 0.960
DEGS1
Delta 4-desaturase, sphingolipid 1.
   
 
 0.960
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
     
 0.959
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.957
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (38%) [HD]